The UK has recorded 214 coronavirus-related deaths and 39,329 cases in the latest 24-hour period.
The number of fatalities is a drop on the 262 reported on Tuesday - and close to the 217 reported last Wednesday.
A total of 142,338 people have now died with COVID in the UK.
The number of cases reported on Wednesday is higher than the figures recorded on Tuesday (33,117) but lower than this time last week (41,299).
Meanwhile, an increase of 39,836 first vaccine doses means a total of 50,336,130 had been delivered in the UK by 8 November. Some 45,894,237 second doses have been delivered, an increase of 21,199.
A combined total of 10,920,416 booster and third doses have also been given, a day-on-day rise of 340,294.
Separate figures published by the Office for National Statistics (ONS) show there have been 167,367 deaths registered in the UK where COVID-19 was mentioned on the death certificate.
The highest number on a single day was 1,484 on 19 January.
The daily toll peaked at 1,461 on 8 April 2020 during the first wave of the virus.
A total of 859 deaths registered in England and Wales in the week ending 29 October mentioned COVID-19 on the death certificate - a rise of 8% on the previous week and the highest figure since the week to 24 September.